new PEGylation alternatives

Enabling more patient friendly routes of administration, reduced immunogenicity and improved pharmacodynamics and pharmacokinetics.

THERAPEUTICS REIMAGINED

Combining the power of computational science, synthetic chemistry and biology, BHS introduces a new era of therapeutic tools that overcome the limitations of PEGylation technology. Biohybrid Solutions’ innovators have developed a proprietary understanding of structure-function interactions between polymers and biological molecules, resulting in new synthetic processes, materials, applications, and therapies. To date, we have created thousands of different NanoArmored proteins™ for a variety of therapeutic applications.

BHS-001

Program: OPH Prophylactic
Indication: Nerve agent exposure
Stage: Preclinical development and advanced testing

  • preclinical

BHS-002

Program: GI Enzyme Replacement Therapy
Indication: Pancreatic enzyme insufficiency
Phase: Development

  • Development

BHS-003

Program: Enabling Immunotherapy
Indication: IgG
Phase: Development

  • Research

OPPORTUNITIES IN THERAPEUTICS

Imagine a new alternative to PEGylation that enables more patient friendly routes of administration, reduced immunogenicity and improved pharmacodynamics and pharmacokinetics.

New peptites or protein delivery platforms and therapeutics (e.g. oral, devices)

Thermostable proteins or peptides

Sensing/responsive proteins/peptides

Novel linker/conjugation chemistries

Alternative to PEGylation to enable lifetime extension

Controlled response for better efficacy

Discover a better solution For therapeutics and protein engineering